[1]UCI Faculty Profile System

   [2]For Faculty [3]Search Tips [4]About

Michael R. Rose

   Picture of Michael R. Rose
   Distinguished Professor & Director of NERE, Ecology & Evolutionary Biology
   School of Biological Sciences
   Ph.D., University of Sussex, 1979, Biology
   Phone: (949) 824-8121, 8198
   Fax: (949) 824-2181
   Email: [5]mrrose@uci.edu
   University of California, Irvine
   Ecology and Evolutionary Biology
   School of Biological Sciences
   Mail Code: 2525
   Irvine, CA 92697
   Research Interests
   Experimental Evolution; Aging; Biological Immortality; Drosophila; Human
   Evolution; Evolution of Sex
   Websites
   [6]The Rose Laboratory Website
   Academic Distinctions
   British Commonwealth Scholar, 1976-1979
   NATO Science Fellow, 1979-1981
   NSERC of Canada University Research Fellow, 1981-1988
   President's Prize (with others) American Society of Naturalists, 1992
   Excellence in Teaching Award, UCI Biological Sciences, 1996
   Busse Prize, World Congress of Gerontology, 1997
   Appointments
   NATO Science Fellow: Laboratory of Genetics, University of
   Wisconsin, Madison, 1979-1981
   Dalhousie University: Assistant
   Prof. of Biology, 1981-1985; Associate
   Professor of Biology, 1985-1988
   University of California, Irvine:
   Associate Professor of Biology, 1986-1990;
   Professor of Biology, 1990-
   University of California, Systemwide:
   Director, Intercampus Research Program
   on Experimental Evolution, 2004-2005;
   Director, Network for Experimental Research on Evolution,
   A University of California Multicampus Research Program, 2006-
   Research Abstract
   On receiving a British Commonwealth Scholarship in 1976, Michael Rose proceeded
   to the University of Sussex for his doctoral studies under the supervision of
   Brian Charlesworth and John Maynard Smith. The subject of his doctoral research
   was the quantitative genetics of aging in Drosophila melanogaster. A N.A.T.O.
   Science Fellowship took Rose to the University of Wisconsin - Madison, in 1979,
   to work with James F. Crow at the Department of Genetics. During this period, he
   began to work out some of the theoretical population genetics behind the
   evolution of life-histories, particularly the concept of "antagonistic
   pleiotropy", a term of his coinage
   A federally-funded research faculty position took Rose to Canada in 1981, where
   he became an Assistant Professor in the Department of Biology, Dalhousie
   University, Halifax, Nova Scotia. There he set up a Drosophila laboratory, as
   well as continuing with theoretical work. He was promoted to Associate Professor
   and tenured in 1985. In addition, Rose published Quantitative Ecological Theory,
   in 1987. While at Dalhousie, Rose pursued postponed aging, beginning with the
   organismal physiology involved, particularly energetic metabolism. This work
   extended aging research in an influential new direction, combining physiology
   with evolution. In particular, Rose and his students showed that resistance to
   various stresses was a key factor in postponed aging; flies with the genetic
   capacity to live longer are better able to resist stress at every adult age. This
   work has opened up new avenues of research on aging, with collaborations between
   physiologists and evolutionists of increasing importance.
   In 1987, Rose returned to the United States to become an Associate Professor at
   the University of California, Irvine. In 1990, Rose was promoted to Professor. In
   1991, his Evolutionary Biology of Aging appeared, a book that ranged from
   mathematical genetics to cell biology. This work offered a view of aging that was
   a complete departure from the views that had dominated the aging field since
   1960. The journal Evolution described the field of gerontology as having become
   "after Rose". In 1997, Rose received the Busse Prize of the World Congress of
   Gerontology. In 1998, his book Darwin's Spectre was published, a popular
   introduction to the history and significance of evolutionary biology. In 2004, a
   compendium of his laboratories' research findings was published as Methuselah
   Flies. His latest books are Experimental Evolution (with T. Garland) and Does
   Aging Stop? (with L.D. Mueller and C.L. Rauser).
   Publications
   Curriculum Vitae: ([7]PDF)
   Selected Publications (From About 300)
   Books (selected)
   L.D. Mueller, C.L. Rauser, & M.R. Rose. 2011. Does Aging Stop? Oxford University
   Press, New York.
   T. Garland & M.R. Rose, Eds. 2009. Experimental Evolution. University of
   California Press, Berkeley.
   M.R. Rose and L.D. Mueller. 2006. Evolution and Ecology of the Organism.
   Prentice-Hall, Upper Saddle River, New Jersey.
   M.R. Rose. 2005. The Long Tomorrow; How Advances in Evolutionary Biology Can Help
   Us Postpone Aging. Oxford University Press, New York.
   M.R. Rose, H.B. Passananti, and M. Matos, Editors. 2004. Methuselah Flies: A Case
   Study in the Evolution of Aging. World Scientific Publishing, Singapore.
   M.R. Rose. 1998. Darwin's Spectre, Evolutionary Biology in the Modern World.
   Princeton University Press, Princeton, N.J.
   M.R. Rose and G.V. Lauder, Editors. 1996. Adaptation. Academic Press, New York.
   M.R. Rose and C.E. Finch, Editors. 1994. Genetics and Evolution of Aging. Kluwer
   Academic Publishers, Dordrecht, the Netherlands.
   M.R. Rose. 1991. Evolutionary Biology of Aging. Oxford University Press, New
   York.
   Reviewed Articles (selected)
   J.N. Kezos, L.G. Cabral, B.D. Wong, B.K. Khou, A. Oh, J.F. Harb, D. Chiem, T.J.
   Bradley, L.D. Mueller, M.R. Rose. 2017. Starvation but not locomotion enhances
   heart robustness in Drosophila. Journal of Insect Physiology 99: 8-14.
   J.L. Graves, K.L. Hertweck, M.A. Phillips, M.V. Han, L.G. Cabral, T.T. Barter,
   L.F. Greer, M.K. Burke, L.D. Mueller, M.R. Rose. 2017. Genomics of parallel
   experimental evolution in Drosophila. Molecular Biology and Evolution 34: 831-42.
   M.R. Rose, L.F. Greer, K.H. Phung, G.A. Rutledge, M.A. Phillips, C.N.K. Anderson,
   & L.D. Mueller. 2017. A Hamiltonian demography of life history. Pp. 40-55 in The
   Evolution of Senescence in the Tree of Life, R. Shefferson et al., Eds. Cambridge
   University Press.
   M.R. Rose, G.A. Rutledge, L.G. Cabral, L.F. Greer, A.L. Canfield, & B.G.
   Cervantes. 2017. Evolution and the future of medicine. Pp. 696-705 in On Human
   Nature, M. Tibayrenc & F.J. Ayala, Eds. Elsevier, San Diego.
   M.A. Phillips, A.D. Long, Z.S. Greenspan, L.F. Greer, M.K. Burke, B.
   Villeponteau, K.C. Matsagas, C.L. Rizza, L.D. Mueller, & M.R. Rose. Genome-wide
   analysis of long-term evolutionary domestication in Drosophila melanogaster.
   2016. Scientific Reports 6: 39281, https://dx.doi.org/10.1038%2Fsrep39281.
   L.D. Mueller, P. Shahrestani, C.L. Rauser & M.R. Rose. 2016. The death spiral:
   Predicting death in Drosophila cohorts. Biogerontology 17: 805-816.
   M.R. Rose, L.G. Cabral, J.N. Kezos, T.T. Barter, M.A. Phillips, B.L. Smith, &
   T.C. Burnham. 2016. Four steps toward the control of aging: Following the example
   of infectious disease. Biogerontology 17: 21-31.
   G.A. Rutledge & M.R. Rose. 2015. An evolutionary analysis of healthspan extension
   using diet: Have we come to the end of the Ponce de Leon Trail? Pp. 265-283 in
   Life Extension: Lessons from Drosophila, A. Vaiserman, A. Moskalev, & E.
   Pasyukova, Eds. Springer.
   M.R. Rose, L.C. Cabral, M.A. Philips, G.A. Rutledge, K.H. Phung, L.D. Mueller, &
   L.F. Greer. 2015. The Great Evolutionary Divide: Two Genomic Systems Biologies of
   Aging. In Aging and Health - A Systems Biology Perspective (ed. By A. Yashin & M.
   Jazwinski, Elsevier), Interdisciplinary Topics in Gerontology 40: 63-73.
   M.R. Rose, G.A. Rutledge, K.H. Phung, M.A. Phillips, L.F. Greer & L.D. Mueller.
   2014. An evolutionary and genomic approach to the challenges and opportunities
   for eliminating aging. Current Aging Science 7: 54-59.
   L.D. Mueller, A. Joshi, M. Santos, & M.R. Rose. 2013. Effective Population Size
   and Evolutionary Dynamics in Outbred Laboratory Populations of Drosophila.
   Journal of Genetics 92: 349-61.
   M.R. Rose, T. Flatt, J.L. Graves, L.F. Greer, D. E. Martinez, M. Matos, L.D.
   Mueller, R.J. Shmookler Reis, & P. Shahrestani. 2012. What is aging? Front. Gene.
   3:134. doi: 10.3389/fgene.2012.00134.
   P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical
   physiological transitions from aging to late life in Drosophila, Rejuv. Res. 15:
   49-58.
   M.R. Rose. 2011. Gods and Darwinists. Quarterly Review of Biology 84(4): 323-328.
   ([8]PDF)
   M.R. Rose, L.D. Mueller, and M.K. Burke. 2011. New experiments for an undivided
   genetics.
   Genetics 188: 1-10. ([9]PDF)
   M.K. Burke, J.P. Dunham, P. Shahrestani, K.R. Thornton, M.R. Rose, and A.D. Long.
   2010. Genome-wide analysis of a long-term evolution experiment with Drosophila.
   Nature, in press. Nature 467:
   587-590. Covered in NY Times article by Nicholas Wade, September 20, 2010:
   "Natural Selection Cuts Broad Swath Through Fruit Fly Genome". ([10]PDF)
   H. Teotónio, I.M. Chelo, M. Bradi?, M.R. Rose & A.D. Long. 2009. Experimental
   evolution reveals natural selection on standing genetic variation. Nature
   Genetics 41: 251-257. Covered in News and Views feature in same issue: Reverse
   evolution and evolutionary memory. M.M. Desai, Nature Genetics 41: 142-143.
   ([11]PDF)
   P. Shahrestani, L.D. Mueller, & M.R. Rose. 2009. Does aging stop? Current Aging
   Science 2: 3-11. ([12]PDF)
   M.R. Rose & J.P. Phelan. 2009. Gods inside. In Voices of Disbelief (Ed. R.
   Blackford & U. Schuklenk, Wiley-Blackwell Press, New York). ([13]PDF)
   M.R. Rose & T. Garland. 2009. Darwin's other mistake. In Experimental Evolution
   (Garland, T., and Rose, M.R., Eds., University of California Press). ([14]PDF)
   C.L. Rauser, L.D. Mueller, M. Travisano, & M.R. Rose. 2009. Evolution of aging
   and late life. In Experimental Evolution (Garland, T., and Rose, M.R., Eds.,
   University of California Press). ([15]PDF)
   M.K. Burke & M.R. Rose. 2009. Experimental evolution with Drosophila. American
   Journal of Physiology: Regulatory, Integrative, and Comparative Physiology 296:
   R1847-R1854. ([16]PDF)
   M.R. Rose. 2009. Adaptation, Aging, and Genomic Information. Aging 1: 444-50.
   ([17]PDF)
   M.R. Rose, M.K. Burke, P. Shahrestani, & L.D. Mueller. 2008. Evolution of ageing
   since Darwin. Journal of Genetics 87: 363-371. ([18]PDF)
   S. Sepulveda, P. Shojaeian, C. L. Rauser, M. Jafari, L. D. Mueller, & M. R. Rose.
   2008. The Relationship between Injury, Stress, and Aging in Drosophila
   melanogaster. Experimental Gerontology 43: 136-145. ([19]PDF)
   M.R. Rose and T.H. Oakley. 2007. The new biology: Beyond the Modern Synthesis.
   Biology Direct 2: epub, 30. ([20]PDF)
   M.R. Rose, C.L. Rauser, G. Benford, M. Matos, & L.D. Mueller. 2007. Hamilton's
   Forces of Natural Selection after forty years. Evolution 61: 1265-1276. ([21]PDF)
   M.A. Archer, T.J. Bradley, L.D. Mueller & M.R. Rose. 2007. Using experimental
   evolution to study the physiological mechanisms of desiccation resistance in
   Drosophila melanogaster. Physiological and Biochemical Zoology 80: 386-398.
   ([22]PDF)
   L.D. Mueller, C.L. Rauser, & M.R. Rose. 2007. An evolutionary heterogeneity model
   of late-life fecundity in Drosophila. Biogerontology 8: 147-161. ([23]PDF)
   W. Van Voorhies, J.W. Curtsinger, & M.R. Rose. 2006. Do longevity mutants always
   show trade-offs? Experimental Gerontology 41: 1055-1058. ([24]PDF)
   J.L. Graves & M.R. Rose. 2006. Against racial medicine. Patterns of Prejudice 40:
   481-493. ([25]PDF)
   M. R. Rose, C.L. Rauser, L.D. Mueller, & G. Benford. 2006. A revolution for aging
   research. Biogerontology 7: 269-277. ([26]PDF)
   C.L. Rauser, L.D. Mueller, & M.R. Rose. 2006. The evolution of late life. Aging
   Research Reviews 5: 14-32. ([27]PDF)
   C.L. Rauser, J.J. Tierney, S. M. Gunion, G. M. Covarrubias, L. D. Mueller, and M.
   R. Rose. 2006. Evolution of late-life fecundity in Drosophila melanogaster.
   Journal of Evolutionary Biology 19: 289-301. ([28]PDF)
   M. R. Rose, C.L. Rauser & L.D. Mueller. 2005. Late life: A new frontier for
   physiology. Physiological and Biochemical Zoology 78: 869-878. ([29]PDF)
   C.L. Rauser, Y. Abdel-Aal, J.A. Shieh, C.W. Suen, L.D. Mueller & M.R. Rose. 2005.
   Lifelong heterogeneity in fecundity is insufficient to explain late-life
   fecundity plateaus in Drosophila melanogaster. Experimental Gerontology 40:
   660-670. ([30]PDF)
   M.R. Rose, H.B. Passananti, A.K. Chippindale, J.P. Phelan, M. Matos, H. Teotónio,
   & L.D. Mueller. 2005. The effects of evolution are local: Evidence from
   experimental evolution in Drosophila. Integrative and Comparative Biology 45:
   486-491. ([31]PDF)
   J.P. Phelan & M.R. Rose. 2005. Why dietary restriction substantially increases
   longevity in animal models but won't in humans. Aging Research Reviews 4:
   339-350. ([32]PDF)
   C.L. Rauser, J.S. Hong, M.B. Cung, K.M. Pham, L.D. Mueller, and M.R. Rose. 2005.
   Testing whether male age or high nutrition causes the cessation of reproductive
   aging in female Drosophila melanogaster populations. Rejuvenation Research 8:
   86-95. ([33]PDF)
   H. Teotónio, M. Matos, and M.R. Rose. 2004. Quantitative genetics of functional
   characters in Drosophila melanogaster populations subjected to laboratory
   selection. J. Genet. 83: 265-277. ([34]PDF)
   M. Matos, P. Simões, A. Duarte, C. Rego, T. Avelar, and M.R. Rose. 2004.
   Convergence to a novel environment - Comparative method versus experimental
   evolution. Evolution 58: 1503-1510. ([35]PDF)
   A.K. Chippindale, A.L. Ngo, & M.R. Rose. 2003. The devil in the details of life
   history evolution: Instability and reversal of genetic correlations during
   selection on Drosophila development. Journal of Genetics 82: 133-145. ([36]PDF)
   J. P. Phelan, M.A. Archer, K.A. Beckman, A.K. Chippindale, T.J. Nusbaum, & M.R.
   Rose. 2003. Breakdown in Correlations During Laboratory Evolution. I. Comparative
   Analyses of Drosophila Populations. Evolution 57: 527-535. ([37]PDF)
   M.A. Archer, J.P. Phelan, K.A. Beckman, & M.R. Rose. 2003. Breakdown in
   Correlations During Laboratory Evolution. II. Selection on Stress Resistance in
   Drosophila Populations. Evolution 57: 536-543. ([38]PDF)
   L.D. Mueller, M.D. Drapeau, C.S. Adams, C.W. Hammerle, K.M. Doyal, A. J.
   Jazayeri, T. Ly, S.A. Beguwala, A.R. Mamidi, & M.R. Rose. 2003. Statistical tests
   of demographic heterogeneity theories. Experimental Gerontology 38: 373-386.
   ([39]PDF)
   M.R. Rose, M.D. Drapeau, P.G. Yazdi, K.H. Shah, D.B. Moise, R.R. Thakar, C. L.
   Rauser, & L. D. Mueller. 2002. Evolution of late-life mortality in Drosophila
   melanogaster. Evolution 56: 1982-1991. ([40]PDF)
   H. Teotónio, M. Matos, & M.R. Rose. 2002. Reverse evolution of fitness in
   Drosophila melanogaster. J. of Evolutionary Biology 15: 608-617. ([41]PDF)
   M. Matos, T. Avelar, & M.R. Rose. 2002. Variation in the rate of convergent
   evolution: adaptation to a laboratory environment in Drosophila subobscura. J. of
   Evolutionary Biology 15: 673-682. ([42]PDF)
   H. Teotónio & M.R. Rose. 2001. Perspective: Reverse evolution. Evolution 55:
   653-660. ([43]PDF)
   M.R. Rose & L.D. Mueller. 2000. Ageing and immortality. Philosophical
   Transactions of the Royal Society, London 355: 1657-1662. ([44]PDF)
   H. Teotónio & M.R. Rose. 2000. Variation in the reversibility of evolution.
   Nature 408: 463-466. ([45]PDF)
   M.D. Drapeau, E.K. Gass, M.D. Simison, L.D. Mueller, & M.R. Rose. 2000. Testing
   the heterogeneity theory of late-life mortality plateaus by using cohorts of
   Drosophila melanogaster. Experimental Gerontology 35: 71-84. ([46]PDF)
   M.R. Rose. 1999. Genetics of aging in Drosophila. Experimental Gerontology 34:
   577-85. ([47]PDF)
   T.J. Bradley, A.E. Williams, & M.R. Rose. 1999. Physiological responses to
   selection for desiccation resistance in Drosophila melanogaster. American
   Zoologist 39: 337-45. ([48]PDF)
   T.J. Nusbaum & M.R. Rose. 1999. The effects of nutritional manipulation and
   laboratory selection on lifespan in Drosophila melanogaster. Journal of
   Gerontology: Biological Sciences 54A: B192-B198. ([49]PDF)
   M.R. Rose. 1998. Darwinian anti-aging medicine. Journal of Anti-Aging Medicine 1:
   105-108. ([50]PDF)
   M.R. Rose & T.J. Bradley. 1998. Evolutionary physiology of the cost of
   reproduction. OIKOS 83: 443-451. ([51]PDF)
   A.K. Chippindale, A.G. Gibbs, M. Sheik, K.J. Yee, M. Djawdan, T.J. Bradley, &
   M.R. Rose. 1998. Resource acquisition and the evolution of stress resistance in
   Drosophila melanogaster. Evolution 52: 1342-52. ([52]PDF)
   M.R. Rose & L.D. Mueller. 1998. Evolution of human lifespan: past, future, and
   present. American Journal of Human Biology 10: 409-420. ([53]PDF)
   A.K. Chippindale, J.A. Alipaz, H-W. Chen, and M.R. Rose. 1997. Experimental
   evolution of accelerated development in Drosophila. 1. Larval development speed
   and survival. Evolution 51: 1536-1551. ([54]PDF)
   A.K. Chippindale, A.M. Leroi, H. Saing, D.J. Borash & M.R. Rose. 1997. Phenotypic
   plasticity and selection in Drosophila life-history evolution. 2. Diet, mates and
   the cost of reproduction. Journal of Evolutionary Biology 10: 269-293. ([55]PDF)
   D.J. Deckert-Cruz, R.H. Tyler, J.E. Landmesser & M.R. Rose. 1997. Allozymic
   differentiation in response to laboratory demographic selection of Drosophila
   melanogaster. Evolution 51: 865-872. ([56]PDF)
   A.G. Gibbs, A.K. Chippindale & M.R. Rose. 1997. Physiological mechanisms of
   evolved desiccation resistance in Drosophila melanogaster. Journal of
   Experimental Biology 200: 1821-1832. ([57]PDF)
   L.D. Mueller & M.R. Rose. 1996. Evolutionary theory predicts late-life mortality
   plateaus. Proc. Natl. Acad. Sci. USA 93: 15249-15253. ([58]PDF)
   M. Djawdan, T. Sugiyama, L. Schlaeger, T.J. Bradley, & M.R. Rose. 1996. Metabolic
   aspects of the trade-off between fecundity and longevity in Drosophila
   melanogaster. Physiological Zoology 69:1175-1195. ([59]PDF)
   T.J. Nusbaum, L.D. Mueller, & M.R. Rose. 1996. Evolutionary patterns among
   measures of aging. Experimental Gerontology 31:507-516. ([60]PDF)
   A.K. Chippindale, T.J.F. Chu & M.R. Rose. 1996. Complex trade-offs and the
   evolution of starvation resistance in Drosophila melanogaster. Evolution
   50:753-66. ([61]PDF)
   L.D. Mueller, T.J. Nusbaum & M.R. Rose. 1995. The Gompertz equation as a
   predictive tool in demography. Experimental Gerontology 30:553-569. ([62]PDF)
   C.E. Finch & M.R. Rose. 1995. Hormones and the physiological architecture of
   life-history evolution. Quarterly Review of Biology 70: 1-52. ([63]PDF)
   A.K. Chippindale, D.T. Hoang, P.M. Service & M.R. Rose. 1994. The evolution of
   development in Drosophila melanogaster selected for postponed senescence.
   Evolution 48: 1880-1899. ([64]PDF)
   A.M. Leroi, A.K. Chippindale & M.R. Rose. 1994. Long-term laboratory evolution of
   a genetic trade-off in Drosophila melanogaster. I. The role of genotype x
   environment interaction. Evolution 48: 1244-1257. ([65]PDF)
   A.M. Leroi, W.R. Chen & M.R. Rose. 1994. Long-term laboratory evolution of a
   genetic trade-off in Drosophila melanogaster. II. Stability of genetic
   correlations. Evolution 48: 1258-1268. ([66]PDF)
   A.M. Leroi, S.B. Kim & M.R. Rose. 1994. The evolution of phenotypic life-history
   trade-offs: an experimental study using Drosophila melanogaster. American
   Naturalist 144:661-676. ([67]PDF)
   M.R. Rose & T.J. Nusbaum. 1994. Prospects for postponing human aging. FASEB
   Journal 8: 925-928. ([68]PDF)
   T.J. Nusbaum & M.R. Rose. 1994. Aging in Drosophila. Comparative Biochemistry and
   Physiology 109A: 33-38. ([69]PDF)
   J.E. Fleming, G.S. Spicer, R.C. Garrison & M.R. Rose. 1993. Two dimensional
   protein electrophoretic analysis of postponed aging in Drosophila. Genetica 91:
   183-198. ([70]PDF)
   L.D. Mueller, J.L. Graves, & M.R. Rose. 1993. Interactions between
   density-dependent and age-specific selection in Drosophila melanogaster.
   Functional Ecology 7:469-479. ([71]PDF)
   G.V. Lauder, A.M. Leroi & M.R. Rose. 1993. Adaptations and history. Trends in
   Ecology and Evolution 8:294-297. ([72]PDF)
   A.K. Chippindale, A.M. Leroi, S.B. Kim, & M.R. Rose. 1993. Phenotypic plasticity
   and selection in Drosophila life-history evolution. I. Nutrition and the cost of
   reproduction. J. Evol. Biology 6:171-193. ([73]PDF)
   M.R. Rose, L.N. Vu, S.U. Park, & J.L. Graves. 1992. Selection for stress
   resistance increases longevity in Drosophila melanogaster. Exp. Gerontol. 27:
   241-250. ([74]PDF)
   J.L. Graves, E.C. Toolson, C. Jeong, L.N. Vu, & M.R. Rose. 1992. Desiccation,
   flight, glycogen, and postponed senescence in Drosophila melanogaster. Physiol.
   Zool. 65:268-286. ([75]PDF)
   T.B.L. Kirkwood & M.R. Rose. 1991. Evolution of senescence: late survival
   sacrificed for reproduction. Phil. Trans. R. Soc. B 332: 15 24. ([76]PDF)
   E.W. Hutchinson & M.R. Rose. 1991. Quantitative genetics of postponed aging in
   Drosophila melanogaster. I. Analysis of outbred populations. Genetics 127: 719
   727. ([77]PDF)
   E.W. Hutchinson, A.J. Shaw & M.R. Rose. 1991. Quantitative genetics of postponed
   aging in Drosophila melanogaster. II. Analysis of selected lines. Genetics 127:
   729 737. ([78]PDF)
   M.R. Rose. 1989. Genetics of increased lifespan in Drosophila. Bioessays 11: 132
   135. ([79]PDF)
   M.R. Rose & J.L. Graves. 1989. What evolutionary biology can do for gerontology.
   J. Gerontology: B27-B29. ([80]PDF)
   P.M. Service, E.W. Hutchinson, & M.R. Rose. 1988. Multiple genetic mechanisms for
   the evolution of senescence in Drosophila melanogaster. Evolution 42: 708-716.
   ([81]PDF)
   D.E. Edmonds & M.R. Rose. 1988. Reproductive wastage and the evolution of genetic
   systems. J. Theor. Biol. 132: 247-250. ([82]PDF)
   M. Krieber & M.R. Rose. 1986. Males, parthenogenesis, and the maintenance of
   anisogamous sex. J. Theor. Biol. 122: 421-440. ([83]PDF)
   C. Tremblay & M.R. Rose. 1985. Population dynamics of gene transfer. Theor. Pop.
   Biol. 28: 359-381. ([84]PDF)
   M.R. Rose. 1985. Life-history evolution with antagonistic pleiotropy and
   overlapping generations. Theor. Pop. Biol. 28: 342-358. ([85]PDF)
   P.M. Service, E.W. Hutchinson, M.D. MacKinley, & M.R. Rose. 1985. Resistance to
   environmental stress in Drosophila melanogaster selected for postponed
   senescence. Physiol. Zool. 58: 380-389. ([86]PDF)
   P.M. Service & M.R. Rose. 1985. Genetic covariation among life history
   components: the effect of novel environments. Evolution 39: 943-945. ([87]PDF)
   R.J. Wassersug & M.R. Rose. 1984. A reader's guide and retrospective to the 1982
   Darwin centennial. Q. Rev. Biol. 59: 417-437. ([88]PDF)
   M.R. Rose. 1984. Laboratory evolution of postponed senescence in Drosophila
   melanogaster. Evolution 38: 1004-1010. ([89]PDF)
   M.R. Rose. 1984. The evolution of animal senescence. Can. J. Zool. 62: 1661-1667.
   ([90]PDF)
   M.R. Rose, M.L. Dorey, A.M. Coyle & P.M. Service. 1984. The morphology of
   postponed senescence in Drosophila melanogaster. Can. J. Zool. 62: 1576-1580.
   ([91]PDF)
   M.R. Rose. 1984. Artificial selection on a fitness-component in Drosophila
   melanogaster. Evolution 38: 516-526. ([92]PDF)
   M.R. Rose. 1984. Genetic covariation in Drosophila life history: untangling the
   data. Am. Nat. 123: 565-569. ([93]PDF)
   M.R. Rose & W.F. Doolittle. 1983. Molecular biological mechanisms of speciation.
   Science 220: 157-162. ([94]PDF)
   M.R. Rose. 1983. The contagion mechanism for the origin of sex. J. Theor. Biol.
   101: 137-146. ([95]PDF)
   M.R. Rose. 1983. Theories of life-history evolution. Am. Zool. 23: 15-23.
   ([96]PDF)
   M.R. Rose. 1983. Hominid evolution and social science. J. Soc. Biol. Struct. 6:
   29-36. ([97]PDF)
   M.R. Rose. 1982. A physiological barrier for the maintenance of anisogamous sex.
   J. Theor. Biol. 94: 801-813 ([98]PDF)
   M.R. Rose. 1982. Antagonistic pleiotropy, dominance, and genetic variation.
   Heredity 48: 63-78. ([99]PDF)
   M.R. Rose & B. Charlesworth. 1981. Genetics of life-history in Drosophila
   melanogaster. II. Exploratory selection experiments. Genetics 97: 187-196.
   ([100]PDF)
   M.R. Rose & B. Charlesworth. 1981. Genetics of life-history in Drosophila
   melanogaster. I. Sib analysis of adult females. Genetics 97: 173-185. ([101]PDF)
   M.R. Rose & R. Harmsen. 1981. Ecological outbreak dynamics and the cusp
   catastrophe. Acta Biotheoretica 30: 239-263. ([102]PDF)
   M. Rose & B. Charlesworth. 1980. A test of evolutionary theories of senescence.
   Nature 287: 141-142. ([103]PDF)
   M.R. Rose. 1980. The mental arms race amplifier. Human Ecol. 8: 285-293.
   ([104]PDF)
   J. Haigh & M.R. Rose. 1980. Evolutionary game auctions. J. Theor. Biol. 85:
   381-397. ([105]PDF)
   M.R. Rose. 1978. Cheating in evolutionary games. J. Theor. Biol. 75: 21-34.
   ([106]PDF)
   Professional Societies
   Member, Society for the Study of Evolution
   Fellow, AAAS
   Research Centers
   Director of the Network for Experimental Research on Evolution (NERE), A
   University of California Multicampus Research Program
   Link to this profile
   [107]https://faculty.uci.edu/profile/?facultyId=5261
   Last updated
   10/02/2018

     * [108]© 2023 The Regents of the University of California |
     * [109]Privacy & Legal Notice |
     * [110]Email FPS Support

References

   Visible links:
   1. https://faculty.uci.edu/
   2. https://faculty.uci.edu/forFaculty
   3. https://faculty.uci.edu/help
   4. https://faculty.uci.edu/about
   5. mailto:mrrose@uci.edu
   6. https://roselab.bio.uci.edu/
   7. http://roselab.bio.uci.edu/Michael_Rose_CV_01-25-2012.pdf
   8. http://roselab.bio.uci.edu/Publications/99%20Rose%202011.pdf
   9. http://roselab.bio.uci.edu/Publications/98%20Rose%20Mueller%20Burke%202011.pdf
  10. http://roselab.bio.uci.edu/Publications/97%20Burke%20Dunham%20Shahrestani%20Thornton%20Rose%20Long%202010.pdf
  11. http://roselab.bio.uci.edu/Publications/96%20Teotonio%20Chelo%20Bradi%20Rose%20Long%202009.pdf
  12. http://roselab.bio.uci.edu/Publications/95%20Shahrestani%20Mueller%20Rose%202009.pdf
  13. http://roselab.bio.uci.edu/Publications/94%20Rose%20Phelan%202009.pdf
  14. http://roselab.bio.uci.edu/Publications/93%20Rose%20Garland%202009.pdf
  15. http://roselab.bio.uci.edu/Publications/92%20Rauser%20Mueller%20Travisano%20Rose%202009.pdf
  16. http://roselab.bio.uci.edu/Publications/91%20Burke%20Rose%202009.pdf
  17. http://roselab.bio.uci.edu/Publications/90%20Rose%202009.pdf
  18. http://roselab.bio.uci.edu/Publications/89%20Rose%20Burke%20Shahrestani%20Mueller%202008.pdf
  19. http://roselab.bio.uci.edu/Publications/88%20Sepulveda%20Shojaeian%20Rauser%20Jafari%20Mueller%20Rose%202008.pdf
  20. http://roselab.bio.uci.edu/Publications/87%20Rose%20Oakley%202007.pdf
  21. http://roselab.bio.uci.edu/Publications/88%20Sepulveda%20Shojaeian%20Rauser%20Jafari%20Mueller%20Rose%202008.pdf
  22. http://roselab.bio.uci.edu/Publications/85%20Archer%20Bradley%20Mueller%20Rose%202007.pdf
  23. http://roselab.bio.uci.edu/Publications/84%20Mueller%20Rauser%20Rose%202007.pdf
  24. http://roselab.bio.uci.edu/Publications/83%20Van%20Voorhies%20Curtsinger%20Rose%202006.pdf
  25. http://roselab.bio.uci.edu/Publications/82%20Graves%20Rose%202006.pdf
  26. http://roselab.bio.uci.edu/Publications/81%20Rose%20Rauser%20Mueller%20Benford%202006.pdf
  27. http://roselab.bio.uci.edu/Publications/80%20Rauser%20Mueller%20Rose%202006.pdf
  28. http://roselab.bio.uci.edu/Publications/79%20Rauser%20Tierney%20Gunion%20Covarrubias%20Mueller%20Rose%202006.pdf
  29. http://roselab.bio.uci.edu/Publications/78%20Rose%20Rauser%20Mueller%202005.pdf
  30. http://roselab.bio.uci.edu/Publications/77%20Rauser%20Abdel-Aal%20Shieh%20Suen%20Mueller%20Rose%202005.pdf
  31. http://roselab.bio.uci.edu/Publications/76%20Rose%20Passananti%20Chippindale%20Phelan%20Matos%20Teotonio%20Mueller%202005.pdf
  32. http://roselab.bio.uci.edu/Publications/75%20Phelan%20Rose%202005.pdf
  33. http://roselab.bio.uci.edu/Publications/74%20Rauser%20Hong%20Cung%20Pham%20Mueller%20Rose%202005.pdf
  34. http://roselab.bio.uci.edu/Publications/73%20Teotonio%20Matos%20Rose%202004.pdf
  35. http://roselab.bio.uci.edu/Publications/72%20Matos%20Simoes%20Duarte%20Rego%20Avelar%20Rose%202004.pdf
  36. http://roselab.bio.uci.edu/Publications/71%20Chippindale%20Ngo%20Rose%202003.pdf
  37. http://roselab.bio.uci.edu/Publications/70%20Phelan%20Archer%20Beckman%20Chippindale%20Nusbaum%20Rose%202003.pdf
  38. http://roselab.bio.uci.edu/Publications/69%20Archer%20Phelan%20Beckman%20Rose%202003.pdf
  39. http://roselab.bio.uci.edu/Publications/68%20Mueller%20Drapeau%20Adams%20Hammerle%20Doyal%20Jazayeri%20Ly%20Beguwala%20Mamidi%20Rose%202003.pdf
  40. http://roselab.bio.uci.edu/Publications/67%20Rose%20Drapeau%20Yazdi%20Shah%20Moise%20Thakar%20Rauser%20Mueller%202002.pdf
  41. http://roselab.bio.uci.edu/Publications/66%20Teotonio%20Matos%20Rose%202002.pdf
  42. http://roselab.bio.uci.edu/Publications/65%20Matos%20Avelar%20Rose%202002.pdf
  43. http://roselab.bio.uci.edu/Publications/64%20Teotonio%20Rose%202011.pdf
  44. http://roselab.bio.uci.edu/Publications/63%20Rose%20Mueller%202000.pdf
  45. http://roselab.bio.uci.edu/Publications/62%20Teotonio%20Rose%202000.pdf
  46. http://roselab.bio.uci.edu/Publications/61%20Drapeau%20Gass%20Simison%20Mueller%20Rose%202000.pdf
  47. http://roselab.bio.uci.edu/Publications/60%20Rose%201999.pdf
  48. http://roselab.bio.uci.edu/Publications/59%20Bradley%20Williams%20Rose%201999.pdf
  49. http://roselab.bio.uci.edu/Publications/58%20Nusbaum%20Rose%201999.pdf
  50. http://roselab.bio.uci.edu/Publications/57%20Rose%201998.pdf
  51. http://roselab.bio.uci.edu/Publications/56%20Rose%20Bradley%201998.pdf
  52. http://roselab.bio.uci.edu/Publications/55%20Chippindale%20Gibbs%20Sheik%20Yee%20Djawdan%20Bradley%20Rose%201998.pdf
  53. http://roselab.bio.uci.edu/Publications/54%20ROse%20Mueller%201998.pdf
  54. http://roselab.bio.uci.edu/Publications/53%20Chippindale%20alipaz%20Chen%20Rose%201997.pdf
  55. http://roselab.bio.uci.edu/Publications/52%20Chippindale%20Leroi%20Saing%20Borash%20Rose%201997.pdf
  56. http://roselab.bio.uci.edu/Publications/51%20Deckert-Cruz%20Tyler%20Landmesser%20Rose%201997.pdf
  57. http://roselab.bio.uci.edu/Publications/50%20Gibbs%20Chippindale%20Rose%201997.pdf
  58. http://roselab.bio.uci.edu/Publications/49%20Mueller%20Rose%201996.pdf
  59. http://roselab.bio.uci.edu/Publications/48%20Djawdan%20Sugiyama%20Schlaeger%20Bradley%20Rose%201996.pdf
  60. http://roselab.bio.uci.edu/Publications/47%20Nusbaum%20Mueller%20Rose%201996.pdf
  61. http://roselab.bio.uci.edu/Publications/46%20Chippindale%20Chu%20Rose%201996.pdf
  62. http://roselab.bio.uci.edu/Publications/45%20Mueller%20Nusbaum%20Rose%201995.pdf
  63. http://roselab.bio.uci.edu/Publications/44%20Finch%20Rose%201995.pdf
  64. http://roselab.bio.uci.edu/Publications/43%20Chippindale%20Hoang%20Service%20Rose%201994.pdf
  65. http://roselab.bio.uci.edu/Publications/42%20Leroi%20Chippindale%20Rose%201994.pdf
  66. http://roselab.bio.uci.edu/Publications/41%20Leroi%20Chen%20Rose%201994.pdf
  67. http://roselab.bio.uci.edu/Publications/40%20Leroi%20Kim%20Rose%201994.pdf
  68. http://roselab.bio.uci.edu/Publications/39%20Rose%20Nusbaum%201994.pdf
  69. http://roselab.bio.uci.edu/Publications/38%20Nusbaum%20Rose%201994.pdf
  70. http://roselab.bio.uci.edu/Publications/37%20Fleming%20Spicer%20Garrison%20Rose%201993.pdf
  71. http://roselab.bio.uci.edu/Publications/36%20Mueller%20Graves%20Rose%201993.pdf
  72. http://roselab.bio.uci.edu/Publications/35%20Lauder%20Leroi%20Rose%201993.pdf
  73. http://roselab.bio.uci.edu/Publications/34%20Chippindale%20Leroi%20Kim%20Rose%201993.pdf
  74. http://roselab.bio.uci.edu/Publications/33%20Rose%20Vu%20Park%20Graves%201992.pdf
  75. http://roselab.bio.uci.edu/Publications/32%20Graves%20Toolson%20Jeong%20Vu%20Rose%201992.pdf
  76. http://roselab.bio.uci.edu/Publications/31%20Kirkwood%20Rose%201991.pdf
  77. http://roselab.bio.uci.edu/Publications/30%20Hutchinson%20Rose%201991.pdf
  78. http://roselab.bio.uci.edu/Publications/29%20Hutchinson%20Shaw%20Rose%201991.pdf
  79. http://roselab.bio.uci.edu/Publications/28%20Rose%201989.pdf
  80. http://roselab.bio.uci.edu/Publications/27%20Rose%20Graves%201989.pdf
  81. http://roselab.bio.uci.edu/Publications/26%20Service%20Hutchinson%20Rose%201988.pdf
  82. http://roselab.bio.uci.edu/Publications/25%20Edmonds%20Rose%201988.pdf
  83. http://roselab.bio.uci.edu/Publications/24%20Krieber%20Rose%201986.pdf
  84. http://roselab.bio.uci.edu/Publications/23%20Trembley%20Rose%201985.pdf
  85. http://roselab.bio.uci.edu/Publications/22%20Rose%201985.pdf
  86. http://roselab.bio.uci.edu/Publications/21%20Service%20Hutchinson%20Mackinley%20Rose%201985.pdf
  87. http://roselab.bio.uci.edu/Publications/20%20Service%20Rose%201985.pdf
  88. http://roselab.bio.uci.edu/Publications/19%20Wassersug%20Rose%201984.pdf
  89. http://roselab.bio.uci.edu/Publications/18%20Rose%201984.pdf
  90. http://roselab.bio.uci.edu/Publications/17%20Rose%201984.pdf
  91. http://roselab.bio.uci.edu/Publications/16%20Rose%20Dorey%20Coyle%20Service%201984.pdf
  92. http://roselab.bio.uci.edu/Publications/15%20Rose%201984.pdf
  93. http://roselab.bio.uci.edu/Publications/14%20Rose%201984.pdf
  94. http://roselab.bio.uci.edu/Publications/13%20Rose%20Doolittle%201983.pdf
  95. http://roselab.bio.uci.edu/Publications/12%20Rose%201983.pdf
  96. http://roselab.bio.uci.edu/Publications/11%20Rose%201983.pdf
  97. http://roselab.bio.uci.edu/Publications/10%20Rose%201983.pdf
  98. http://roselab.bio.uci.edu/Publications/9%20Rose%201982.pdf
  99. http://roselab.bio.uci.edu/Publications/8%20Rose%201982.pdf
 100. http://roselab.bio.uci.edu/Publications/7%20Rose%20Charlesworth%201981.pdf
 101. http://roselab.bio.uci.edu/Publications/6%20Rose%20Charlesworth%201981.pdf
 102. http://roselab.bio.uci.edu/Publications/5%20Rose%20Harmsen%201981.pdf
 103. http://roselab.bio.uci.edu/Publications/4%20Rose%20Charlesworth%201980.pdf
 104. http://roselab.bio.uci.edu/Publications/3%20Rose%201980.pdf
 105. http://roselab.bio.uci.edu/Publications/2%20Haigh%20Rose%201980.pdf
 106. http://roselab.bio.uci.edu/Publications/1%20Rose.pdf
 107. https://faculty.uci.edu/profile/?facultyId=5261
 108. https://uci.edu/copyright/
 109. https://research.uci.edu/privacy-policy-2/
 110. mailto:or-web-support@uci.edu

   Hidden links:
 112. javascript:void(0);